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Can an M1 16GB Mac run Qwen2.5 72B?

M1 · 16 GB unified memory · 68 GB/s · MacBook Air (M1), Mac mini (M1)

No — not at Q4_K_M.

Qwen2.5 72B needs about 46.8 GiB but an M1 16GB Mac has only ~13.0 GiB available for a model — you are 33.8 GiB short. macOS will swap to SSD and generation will crawl.

Weights
41.5 GiB
72.7B params @ Q4_K_M
KV cache
2.5 GiB
8K context, FP16
Overhead
2.9 GiB
runtime + activations
Total needed
46.8 GiB
of ~13.0 GiB usable
Est. speed
1 tok/s
68 GB/s bandwidth
Max context
n/a
at Q4_K_M

Where the memory goes

Three things occupy memory when a model is loaded: the weights themselves, the KV cache that holds the conversation, and the runtime's own working buffers. Only the first is fixed — the KV cache grows with every token in your context.

QuantisationWeightsTotalTok/sFits?
FP16135.4 GiB145.5 GiB0No
Q8_071.9 GiB78.8 GiB1No
Q6_K55.9 GiB62.0 GiB1No
Q5_K_M48.2 GiB54.0 GiB1No
Q4_K_M41.5 GiB46.8 GiB1No
Q3_K_M33.0 GiB38.0 GiB2No
Q2_K25.4 GiB30.0 GiB2No

The default. Best quality-per-gigabyte for most people.

How long a context fits

The KV cache is often what breaks a setup that looked fine at load time. Quantising it to 8-bit roughly halves its footprint with little measurable quality cost.

ContextKV cacheTotalFP16 KVQ8 KV
2K0.6 GiB44.7 GiBNoNo
4K1.3 GiB45.4 GiBNoNo
8K2.5 GiB46.8 GiBNoNo
16K5.0 GiB49.6 GiBNoNo
32K10.0 GiB55.2 GiBNoNo
128K40.0 GiB88.8 GiBNoNo

What to run instead on an M1 16GB Mac

These are the largest models that fit comfortably on this machine at Q4_K_M with an 8K context.

ModelSizeTotalTok/s
Qwen3 14B14.8B10.9 GiB6Yes, comfortably
Gemma 2 9B9.24B9.0 GiB10Yes, comfortably
Qwen3 8B8.2B6.8 GiB11Yes, comfortably
Llama 3.1 8B8.03B6.6 GiB11Yes, comfortably
DeepSeek-R1-Distill-Qwen-7B7.62B5.8 GiB12Yes, comfortably
Qwen2.5 7B7.62B5.8 GiB12Yes, comfortably

Macs that run Qwen2.5 72B comfortably

The smallest configuration that handles it is the M2 Max 96GB (MacBook Pro 16" (M2 Max)).

MacMemoryBandwidthTok/s
M2 Max 96GB96 GB400 GB/s7
M3 Ultra 96GB96 GB819 GB/s15
M3 Max 128GB128 GB400 GB/s7
M4 Max 128GB128 GB546 GB/s10
M2 Ultra 192GB192 GB800 GB/s14
M3 Ultra 256GB256 GB819 GB/s15
M3 Ultra 512GB512 GB819 GB/s15

Common questions

Can an M1 16GB Mac run Qwen2.5 72B?
No. At Q4_K_M it needs about 46.8 GiB, and an M1 16GB Mac has roughly 13.0 GiB available for a model after macOS takes its share.
How fast is Qwen2.5 72B on an Mac?
Around 1 tokens per second. Token generation on Apple Silicon is limited by memory bandwidth, and this machine has 68 GB/s.
How much memory does Qwen2.5 72B need?
41.5 GiB for the weights at Q4_K_M, plus 2.5 GiB for an 8K-token KV cache and about 2.9 GiB of runtime overhead — 46.8 GiB in total.